Stand-up comedian Louie  Anderson created and produced a Saturday morning 
animated series for Fox called Life With Louie in 1995. He has written three 
books,and was the initial host of the second revival of the ABC-TV game show
Family Feud, from 1999 to 2002.

Anderson with his cartoon character ‘Louie’

Henry Enrique "Erik" Estrada is best  known for his co-starring lead role in  
the 1977–1983 NBC television series CHiPs. The show followed the lives
of two motorcycle police officers of the California Highway Patrol. Erik has 
recently made appearances in reality TV shows and infomercials and is a  
regular voice on the Cartoon Network.

Erik Estrada with co-star Larry Wilcox in CHiPs

“Uncle Sam” first appeared as a cartoon figure (above) in the New York Lantern weekly newspaper. It was drawn by Frank Henry Bellew (pictured below).
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Cartoonist Frank H. Bellew

The Small Fry Club, also known as Movies for Small Fry, was one of the earliest TV series made for children. It aired until June 15, 1951 on the DuMont Television Network  
and was hosted by "Big Brother Bob Emery" (shown below).The Small Fry Club originally aired weekly, but soon expanded to five days a week. According to television historians, it was possibly the first television series to air five days per week. Before it was on TV, the show got its start on radio, in Boston, Massachusetts.

Big Brother Bob Emery (real name Clair Robert Emery)

Bob Emery (left) with quests Kukla, Fran and Ollie