Mister Ed is a situation comedy produced by Filmways that
first aired in syndication from January 5 to July 2, 1961, and
then on CBS from October 1, 1961 to February 6, 1966.

 

Jacob Joachim "Jack" Klugman (April 27, 1922 – December 24, 2012)

Klugman died at his home in Northridge, California. He was diagnosed with throat
cancer in 1974 and lost a vocal cord to cancer in 1989, but continued to act. The
exact cause of his death is not known. 

He was best known as Felix Unger‘s sloppy roommate Oscar Madison in the ABC
television series The Odd Couple (1970–1975), for his starring role in Quincy, M.E.
on NBC-TV (1976–1983), as Juror #5 in 12 Angry Men, and multiple appearances
on The Twilight Zone.

Barry Livingston is best known for playing little Ernie on 
the ABC/CBS television show "My Three Sons” from 1960
to 1972.

Ray (Herman) Walston (December 2, 1914 – January 1, 2001)

Walston was an stage, television and film actor best known as the
title character on the CBS situation comedy My Favorite Martian from
1963 to 1966.

Harold Peary as Throckmorton Philharmonic Gildersleeve, on the NBC
radio show The Great Gildersleeve. It aired August 31, 1941 to 1957. It
was one of broadcast history’s earliest spin-off programs having been
a staple on the classic radio sitcom Fiber McGee and Molly.

During the show’s 1950 summer hiatus, Peary had contracted with CBS
radio and was legally unable to appear on NBC as a star performer, thus
prompting the hiring of Willard Waterman as Peary’s replacement. 

This was one of the last episodes of the radio series.